M2-Polarized Macrophages Compose Lupus Vulgaris Arising from a Bacillus Calmette-Guérin Vaccination Site

نویسندگان

  • Yota Sato
  • Taku Fujimura
  • Sadanori Furudate
  • Aya Kakizaki
  • Osamu Iizawa
  • Setsuya Aiba
چکیده

Since bacillus Calmette-Guérin (BCG) is an attenuated strain of Mycobacterium bovis, lupus vulgaris (LV) is reported as one of the rare complications after BCG vaccination, correlating with immunosuppression in the lesional skin. In this report, we describe a case of LV arising from the BCG vaccination site 22 years after vaccination. Interestingly, in the present case, granuloma cells were composed of M2-polarized macrophages. Our case might explain the contribution of M2-polarized macrophages to the biology of LV arising from a BCG vaccination site.

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2016